Biomagnetism in patients with CNS disorters

The methods employed in CNS diagnostics are collectively referred to as "Neuroimaging" .The Neuroimaging includes procedures for investigating both cerebral morphology and cerebral function. Such diagnostics are Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), and Single-Photon Emission Computed Tomography (SPECT). On the other hand topographic mapping of electroencephalograms (EEG), evoked potentials and magnetic fields represent the most important topographic functional procedures. The latter applications include not only magnetic fields evoked by stimuli relating to different sensory modalities, but also endogenous and motor fields resulting from spontaneous brain magnetic activity .Such brain magnetic activity can be recorded using SQUID technology and it is called Magnetoencephalograms (MEG) which is the complement of the EEG.The advantage of recording electric and magnetic fields over other neuroimaging procedures is that those techniques are completely noninvasive and have extremely short analyses times. In the list of publications which is followed after this introduction we would like to demonstrate the importance of magnetoencephalography (MEG) as diagnostic procedure used in patients with CNS disorders. Furthermore some relevant publications are also listed utilizing the MEG diagnostic technique in conjuction with the application of extremely low magnetic fields in order to ameliorate CNS dysfunctions.

1. Ph. Anninos, A. Kotini, A. Adamopoulos, N. Tsagas and J. Jacobson
   Nonlinear Analysis of EMG Activity Recorded In Alzheimer Patients
   In Hardronic Journal Supplement 15, 1-16 (2000)
   
   
2. M. G. Manolas, Th. D. Stamoulos, P.A. Anninos
   Differences in human visual evoked potential during the perception of colour as reveald by bootstrap to compare cortical activity. A prospective study.
   Neuroscience Letters 269 (1999) 1-4
   
   
3. P..A. Anninos, N. Tsagas and A. Kotini [1998]
   Magnetic stimulation to patients with CNS dysfunctions.
   Honorary volume for Prof. D.D. Raftopoulos
   E.E. Gdoutos (Ed).
   Research Committee. School of Engineering
   Demokritus University of Thrace. Xanthi, Greece.
   
   
4. Anninos, N. Tsagas , J.Jacobson, A. Kotini [1999]
   The biological effects of magnetic stimulation in epileptic patients.
   Panminerva Medica vol.41, 207-215.
   
   
5. Anninos P.A., Jacobson J., Tsagas N., AdamopoulosA. [1997]
   Spatiotemporal stationarity of epileptic focal activity evalueted by analyzing magnetoencephalographic (MEG) data and the theoretical implications.
   Panminerva med , 39, 189-201
   
   
6. Anninos,P.A., Tsagas, N. [1993]
   Behavior of epileptic patients after magnetic stimulation
   The Neurobehavioral treatment of epilepsy.
   D. Mostofsky and Y. Loyning (Eds). Laurence Erlbaun assoc., publishers pp. 197-217.
   
   
7. Anninos,P.A., Adamopoulos,A., Razis, N., Derpapas,K. [1992]
   MEG measurements using SQUID to localize epileptic foci.
   Normal Matrix and Pathological Conditions, pp. 129- 136.
   Proceedings of Second International Congress of the Society for Matrix Research, Alexandroupolis, Greece, 1990.
   Heine, H. & Anastasiadis, P., (eds.), Gustav Fischer Stuttgart, 1992.
   
   
8. Sandyk, R., Anninos, P.A. [1992]
   Attenuation of epilepsy with application of external magnetic fields.
   Intern. J. Neurosci., 66, (1-2), 75-85
   
   
9. Sandyk,R., Anninos,P.A., Tsagas,N. [1992]
   Magnetic fields alter the circadian periodicity of seizures.
   International Journal of Neuroscience, 63, (3-4), 265-274
   
   
10. Sandyk,R., Anninos,P.A., Tsagas,N., Derpapas,K. [1992]
    Magnetic fields in the treatment of Parkinson's disease : A case report.
    International Journal of Neuroscience vol.63, 141-150.
    
    
11. Sandyk,R., Tsagas,N., Anninos,P.A. [1992]
    Melatonin as a proconvulsive hormone in humans.
    International Journal of Neuroscience vol63, 125-135.
    
    
12. Sandyk,R., Tsagas,N., Anninos,P.A., Derpapas,K. [1992]
    Magnetic fields mimic the behavioral effects of REM sleep deprivation in humans.
    International Journal of Neuroscience 65(1-4), 61-68.
    
    
13. Thodis, E., Anninos, P.A., Pasadakis, P., Adamopoulos, A., Panagoutsos,S., Vargemezis, V. [1992]
    Evaluation of CNS- fuction in CAPD patients using Magnetoencephalography (MEG). Comparison with Hemodialysis Patients.
    Advances in Peritoneal Dialysis, pp.181-184
    
    
14. Anninos,P.A., Tsagas,N, Sandyk,R and Derpapas,K.[1991]
    Magnetic stimulation in the treatment of partial seizures.
    Inter.J.Neuroscience, Vol 60, pp.141-171
    
    
15. Sandyk R, Anninos PA, Tsagas N, Derpapas K
    Pineal calcification and anticonvulsant responsiveness to artificial magnetic stimulation in epileptic patients
    Inter.J.Neuroscience, Vol 60, pp.173-175
    
    
16. Sandyk,R., Anninos,P.A., Tsagas,N. [1991]
    Magnetic fields and seasonality of affective illness: implications for therapy.
    International Journal of Neuroscience, vol.58, 261-267
    
    
17. Sandyk,R., Anninos,P.A., Tsagas,N. [1991]
    Age-related disruption of circadian rhythms : possible relationship to memory impairment and implications for therapy with magnetic fields.
    International Journal of Neuroscience, vol.59, 259-262
    
    
18. Sandyk,R., Anninos,P.A., Tsagas,N. [1991]
    Magnetic fields and the habenular complex.
    International Journal of Neuroscience, vol.59, 263-266
    
    
19. Anninos,P.A., Tsagas,N., Adamopoulos,A., Piperidou,X. [1990]
    Magnetic treatment of epileptic patients by the use of MEG measurements.
    Normal Matrix and Pathological Conditions, pp. 119- 128.
    Proceedings of Second International Congress of the Society for Matrix Research, Alexandroupolis, Greece, 1990.
    Heine, H. & Anastasiadis, P., (eds.), Gustav Fischer Stuttgart, 1992.
    
    
20. Anninos,P.A., Anastasiadis,P., Tsagas,N. [1989]
    Biomagnetic measurements using the biomagnetometer SQUID.
    Proceedings of the Internationaler Kongress der Gesellschaft fur Matrixforschung, October 13-16, in Wittmund, Germany, Gustav Fischer Verlag,pp. 137-149
    
    
21. Anninos,P.A., Razis-Alexandratos, N., Androulakis, I., Vartzopoulos, I., & Adamopoulos, A., [1989]
    The MEG superiority with respect to the EEG in epilepsy studies in children.
    Medical Communication, Volume 1, part 1, pp. 42-45.
    
    
22. Anninos,P.A., Tsagas,N. [1989]
    Localization and cure of epileptic foci with the use of MEG measurements.
    International Journal of Neuroscience, 46, p.p.235-242
    
    
23. Anninos,P.A., Vartzopoulos,J., Razis-Alexandratos,N., Anogianakis,G.[1989]
    Evaluation of epileptic patients with the use of Magnetoencephalogram.
    International Journal of Neuroscience, 45[3-4], 283- 289
    
    
24. Lehnertz,K., Elger,C.E., Hoke,M., Pantev,C., Lutkenhoner,B., Anninos,P.A., Anogianakis,G. [1989]
    Two-Dimensional spectral analysis of MEG data in epileptic patients.
    Advances in epileptology,Vol.17,pages 58-62
    
    
25. Razis-Alexandtratos, N., Anninos, P.A., & Adamopoulos, A. [1989]
    MEG studies in posttraumatic epilepsies.
    Medical Communication, vol. 1, part 2, pp.168-171
    
    
26. Razis-Alexandratos, N., Anninos, P.A., Adamopoulos, A., & Androulakis, I. [1989]
    The differentiation of posttraumatic generalized epilepsies using MEG measurements.
    Medical communication, vol. 1, part 4, pp.344-350
    
    
27. Anogianakis,G., Anninos,P.A. [1988]
    Localization of epileptiform foci by means of MEG measurements.
    International Journal of Neuroscience, 38,141
    
    
28. Elger,C.E., Lehnertz,K., Hoke,M., Pantev,C., Lutkenhoner,B., Anninos,P.A., Anogianakis,G. [1988]
    Mapping of the amplitude spectra:Its significance for the diagnosis of focal epilepsy.
    In:K.Maurer [Ed.],Topographic Brain Mapping of EEG and Evoked Potentials, Springer-Verlag, Berlin, Heidelberg, pp.565-570
    
    
29. Anninos,P.A., Anogianakis,G., Lehnertz,K., Pantev,C., Hoke,M. [1987]
    Biomagnetic measurements using SQUID.
    International Journal of Neuroscience, Vol.37, pp.149
    
    
30. Hoke,M., Elger,C.E., Lehnertz,K., Pantev,C., Lutkenhoner,B., Anogianakis,G., Anninos,P.A. [1987]
    Epileptic activity analyzed by two dimensional spectral analysis of MEG data.
    In Atsumi,K., Kotani,M., Veno,S., Katila,T., Williamson,S.J. [Eds.],Biomagnetism '87,Denki University Press, Tokyo, p.210-213
    
    
31. Anninos,P.A.,Kokkinidis,M. [1986]
    MEG measurements with SQUID as a diagnostic tool for epileptic patients
    Brain Research Bulletin,vol.16,pp.549-551
    
    
32. Anninos,P.A., & Anogianakis, G. [1986]
    Identification and localization of epileptic foci with the use of MEG measurements.
    Proceedings of the North-Greek Medical Conference, Thessalonica, Greece, Volume B.
    
    
33. Anninos,P.A., Kokkinidis,M., Hoke,M., Pantev,C., Lehnertz, K., and Lutkenhoner, B. [1986]
    MEG measurements with SQUID as a diagnostic tool for epileptic patients.
    Brain Research Bulletin, vol.16, pp.549-551
    
    
34. Anninos,P.A. [1985]
    Brain biomagnetic field measurements using the SQUID device.
    Greek Neuroscience Conference in Patras, Greece, 25 - 27 October, 1985.
    
    
35. Tetenes,P.J., Anninos,P.A. [1977]
    Filling of Microelectrodes:an expedient solution Brain Research Bulletin 2, 55-56

This page was updated on the 25-05-2000